Drug Interactions: May potentiate antidiabetic (hypoglycemic) drugs. Due to the cardioactive chemicals in this herb the following drug interactions are possible: interference and/or antagonism with antiarrhythmics; antagonism of beta-adrenoceptor blocking drugs; potentiation of cardiac glycosides and increased risk of hypokalemia; when combined with depolarizing muscle relaxants there is a risk of arrhythmia; interference with nitrates and calcium-channel blockers; may increase the potential terfenadine has to cause arrhythmias. Due to the antihypertensive (hypotensive) action of this herb the following interactions are possible: when taken with anesthetics an increased hypotensive effect; potentiation of antihypertensives; when taken with diuretics difficulty with diuresis and hypertension may result; antagonism of sympathomimetics.